Deepak D’Souza: Perils of Cannabis and Promise of Psychedelics

Deepak D'Souza, the Vikram Sodhi ’92 Professor of Psychiatry at Yale, explains risks from highly potent cannabinoids and research on treating mental health conditions with psychedelics. Harlan reports on efforts to understand the neuroscience around artificial sweeteners. Howie highlights insights from a physician pay survey.

Links:

Artificial Sweeteners

"WHO advises not to use non-sugar sweeteners for weight control in newly released guideline"

"Non-caloric sweetener effects on brain appetite regulation in individuals across varying body weights"

"Artificial sweetener found in diet drinks linked to brain changes that increase appetite, study finds"

"Why One Cardiologist Has Drunk His Last Diet Soda"

Cannabis

"Marijuana: Rising THC Concentrations in Cannabis Can Pose Health Risks"

"Cannabis and Driving"

"CBD vs. THC: What's the Difference?"

"The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis"

"Rapid Changes in CB1 Receptor Availability in Cannabis Dependent Males after Abstinence from Cannabis"

"Cannabidiol (CBD): What we know and what we don't"

"FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy"

"Jacques Joseph Moreau (1804–1884)"

"Cannabis and psychosis: revisiting a nineteenth century study of 'Indian Hemp and Insanity' in Colonial British India"

"Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction"

"The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study"

"Association of Cannabis Use During Adolescence With Neurodevelopment"

"The endocannabinoid system: Essential and mysterious"

Dronabinol: MedlinePlus

Dr. D’Souza

"D’Souza named Vikram Sodhi Professor of Psychiatry"

"CT Yale researcher gets $3 million chair to study DMT use for depression, PTSD"

Physician Pay

"Comparing Your Pay Against Your Peers’: Medscape Physician Compensation Report 2025"

"Physician compensation rose 3.6% in 2024, but not all specialties got a raise"

"Biggest Match Day ever: Here’s what the 2025 numbers reveal"

"Ryan Schwarz: Thinking Differently about the Primary Care Crisis"

Learn more about the MBA for Executives program at Yale SOM.
Email Howie and Harlan comments or questions.